Influences of Realgar-Indigo naturalis, A Traditional Chinese Medicine Formula, on the Main CYP450 Activities in Rats Using a Cocktail Method

The purpose of this work was to study the influences of Realgar-Indigo naturalis (RIF) and its principal element realgar on 4 main cytochrome P450 enzymes activities in rats. A simple and efficient cocktail method was developed to detect the four probe drugs simultaneously. In this study, Wistar rat...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2017-01, Vol.2017 (2017), p.1-9
Hauptverfasser:	Liang, Qian-De, Gao, Yue, Ma, Zengchun, Tang, Xiang-Lin, Wang, Yuguang, Tan, Hongling, Li, Ming, Ren, Si-Jia, Wang, Mei-Xi, Hao, Fei-Ran, Xu, Huanhua, Xiao, Chengrong
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical properties Chinese medicine Complications and side effects Cytochrome Cytochrome P-450 Drug dosages Drugs Enzymes Health aspects Leukemia Medicine, Chinese Metabolism Pharmacokinetics Pharmacology, Experimental Physiological aspects Rodents Studies Sulfide minerals
Online-Zugang:	Volltext
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