VEGF as a Paracrine Regulator of Conventional Outflow Facility

Vascular endothelial growth factor (VEGF) regulates microvascular endothelial permeability, and the permeability of Schlemm's canal (SC) endothelium influences conventional aqueous humor outflow. We hypothesize that VEGF signaling regulates outflow facility. We measured outflow facility (C) in...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2017-03, Vol.58 (3), p.1899-1908
Hauptverfasser:	Reina-Torres, Ester, Wen, Joanne C, Liu, Katy C, Li, Guorong, Sherwood, Joseph M, Chang, Jason Y H, Challa, Pratap, Flügel-Koch, Cassandra M, Stamer, W Daniel, Allingham, R Rand, Overby, Darryl R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aqueous Humor - metabolism Cells, Cultured Humans Intraocular Pressure - physiology Male Mice Mice, Inbred C57BL Models, Animal Ocular Hypertension - metabolism Ocular Hypertension - pathology Ocular Hypertension - physiopathology Physiology and Pharmacology Trabecular Meshwork - cytology Trabecular Meshwork - metabolism Vascular Endothelial Growth Factor A - secretion
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