Trifluoroselenomethionine - a New Non-Natural Amino Acid

Trifluoroselenomethionine (TFSeM), a novel non-natural amino acid, was synthesized in seven steps from N -( tert -butoxycarbonyl)-L-aspartic acid tert -butyl ester. TFSeM shows enhanced methioninase-induced cytotoxicity toward human colon cancer derived HCT-116 cells compared to selenomethionine (Se...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2016-09, Vol.17 (18), p.1738-1751
Hauptverfasser: Block, Eric, Booker, Squire J., Flores-Penalba, Sonia, George, Graham, Gundala, Sivaji, Landgraf, Bradley J., Liu, Jun, Lodge, Stephene N., Pushie, M. Jake, Rozovsky, Sharon, Vattekkatte, Abith, Yaghi, Rama, Zeng, Huawei
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Sprache:eng
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