Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?

Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway has been identified as a molecular feature common to several well-characterized syndromes with high preval...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2017-03, Vol.18 (3), p.659-659
Hauptverfasser:	Magdalon, Juliana, Sánchez-Sánchez, Sandra M, Griesi-Oliveira, Karina, Sertié, Andréa L
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Autism Autism Spectrum Disorder - genetics Autism Spectrum Disorder - metabolism Autism Spectrum Disorder - pathology Brain Cyclin-dependent kinases Etiology Humans Kinases Mechanistic Target of Rapamycin Complex 1 Multiprotein Complexes - genetics Multiprotein Complexes - metabolism Mutation Neurons Pathogenesis Proteins Rapamycin Review Signal Transduction TOR protein TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!