Nrf2 Regulates the Risk of a Diesel Exhaust Inhalation-Induced Immune Response during Bleomycin Lung Injury and Fibrosis in Mice

The present study investigated the effects of diesel exhaust (DE) on an experimental model of bleomycin (BLM)-induced lung injury and fibrosis in mice. BLM was intravenously administered to both and C57BL/6J mice on day 0. The mice were exposed to DE for 56 days from 28 days before the BLM injection...

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Veröffentlicht in:	International journal of molecular sciences 2017-03, Vol.18 (3), p.649-649
Hauptverfasser:	Li, Ying-Ji, Shimizu, Takako, Shinkai, Yusuke, Hirata, Yukiyo, Inagaki, Hirofumi, Takeda, Ken, Azuma, Arata, Yamamoto, Masayuki, Kawada, Tomoyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bleomycin - toxicity Cytokines - metabolism Fibrosis Hydroxyproline - metabolism Lung Injury - etiology Lung Injury - genetics Lung Injury - immunology Lung Injury - pathology Mice Mice, Inbred C57BL NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Oxidative Stress Vehicle Emissions - toxicity
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