Characterization of T Cells Specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-Infected Mauritian Cynomolgus Macaques

Nonhuman primates can be used to study host immune responses to Mauritian cynomolgus macaques (MCMs) are a unique group of animals that have limited major histocompatibility complex (MHC) genetic diversity, such that MHC-identical animals can be infected with Two MCMs homozygous for the relatively c...

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Veröffentlicht in:	Infection and immunity 2017-04, Vol.85 (4)
Hauptverfasser:	Ellis, Amy, Balgeman, Alexis, Rodgers, Mark, Updike, Cassaundra, Tomko, Jaime, Maiello, Pauline, Scanga, Charles A, O'Connor, Shelby L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Bacterial - chemistry Antigens, Bacterial - genetics Antigens, Bacterial - immunology Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - immunology Cynomolgus Disease Models, Animal Epitopes, T-Lymphocyte - chemistry Epitopes, T-Lymphocyte - immunology Histocompatibility Antigens - genetics Histocompatibility Antigens - immunology Histocompatibility Antigens Class II - chemistry Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology Host Response and Inflammation Humans Interferon-gamma - biosynthesis Macaca Macaca fascicularis Mycobacterium tuberculosis Mycobacterium tuberculosis - immunology Peptides - chemistry Peptides - immunology Positron Emission Tomography Computed Tomography T-Lymphocytes - immunology T-Lymphocytes - metabolism Tomography, X-Ray Computed Tuberculosis - diagnosis Tuberculosis - immunology Tuberculosis - metabolism Tuberculosis - microbiology
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