BMP signaling and its paradoxical effects in tumorigenesis and dissemination

Bone morphogenetic proteins (BMPs) play important roles in embryonic and postnatal development by regulating cell differentiation, proliferation, motility, and survival, thus maintaining homeostasis during organ and tissue development. BMPs can lead to tumorigenesis and regulate cancer progression i...

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Veröffentlicht in:	Oncotarget 2016-11, Vol.7 (47), p.78206-78218
Hauptverfasser:	Zhang, Lijie, Ye, Yingnan, Long, Xinxin, Xiao, Pei, Ren, Xiubao, Yu, Jinpu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Proteins - metabolism Carcinogenesis Cell Differentiation Cell Transformation, Neoplastic Epithelial-Mesenchymal Transition Humans Neoplastic Stem Cells - metabolism Review Signal Transduction
Online-Zugang:	Volltext
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