GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients

Genetic polymorphisms are associated with breast cancer risk. Clinical and epidemiological observations suggest that clinical characteristics of breast cancer, such as estrogen receptor or HER2 status, are also influenced by hereditary factors. To identify genetic variants associated with pathologic...

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Veröffentlicht in:	Oncotarget 2016-11, Vol.7 (47), p.77358-77364
Hauptverfasser:	Cox, David G, Curtit, Elsa, Romieu, Gilles, Fumoleau, Pierre, Rios, Maria, Bonnefoi, Hervé, Bachelot, Thomas, Soulié, Patrick, Jouannaud, Christelle, Bourgeois, Hugues, Petit, Thierry, Tennevet, Isabelle, Assouline, David, Mathieu, Marie-Christine, Jacquin, Jean-Philippe, Lavau-Denes, Sandrine, Darut-Jouve, Ariane, Ferrero, Jean-Marc, Tarpin, Carole, Lévy, Christelle, Delecroix, Valérie, Trillet-Lenoir, Véronique, Cojocarasu, Oana, Meunier, Jérôme, Pierga, Jean-Yves, Faure-Mercier, Céline, Blanché, Hélène, Sahbatou, Mourad, Boland, Anne, Bacq, Delphine, Besse, Céline, Deleuze, Jean-François, Pauporté, Iris, Thomas, Gilles, Pivot, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor Breast Neoplasms - genetics Cancer Clinical Trials, Phase III as Topic Cohort Studies Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Life Sciences Polymorphism, Single Nucleotide Randomized Controlled Trials as Topic Receptor, ErbB-2 - genetics Receptor, Fibroblast Growth Factor, Type 2 - genetics Receptors, Estrogen - genetics Research Paper Santé publique et épidémiologie
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