A Genetic Screen Reveals that Synthesis of 1,4-Dihydroxy-2-Naphthoate (DHNA), but Not Full-Length Menaquinone, Is Required for Listeria monocytogenes Cytosolic Survival

Through unknown mechanisms, the host cytosol restricts bacterial colonization; therefore, only professional cytosolic pathogens are adapted to colonize this host environment. is a Gram-positive intracellular pathogen that is highly adapted to colonize the cytosol of both phagocytic and nonphagocytic...

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Veröffentlicht in:	mBio 2017-03, Vol.8 (2)
Hauptverfasser:	Chen, Grischa Y, McDougal, Courtney E, D'Antonio, Marc A, Portman, Jonathan L, Sauer, John-Demian
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Transposable Elements Genetic Testing Listeria monocytogenes - genetics Listeria monocytogenes - physiology Metabolic Networks and Pathways - genetics Microbial Viability Mutagenesis, Insertional Mutation Naphthols - metabolism Vitamin K 2 - metabolism
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