Intraarterial transplantation of human umbilical cord blood mononuclear cells in hyperacute stroke improves vascular function

Human umbilical cord blood (hUCB) cell therapy is a promising treatment for ischemic stroke. The effects of hyperacute stem cell transplantation on cerebrovascular function in ischemic stroke are, however, not well understood. This study evaluated the effects of hyperacute intraarterial transplantat...

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Veröffentlicht in:	Stem cell research & therapy 2017-03, Vol.8 (1), p.74-74, Article 74
Hauptverfasser:	Huang, Lei, Liu, Yichu, Lu, Jianfei, Cerqueira, Bianca, Misra, Vivek, Duong, Timothy Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Biomarkers - metabolism Blood flow Blood Flow Velocity Bone marrow Brain Ischemia - metabolism Brain Ischemia - pathology Brain Ischemia - therapy Carbon dioxide Carotid arteries Carotid artery Carotid Artery, Internal Cell Differentiation Cell Separation Cerebral blood flow Cerebrovascular Circulation Cerebrovascular system Cord blood Cytology Disease Models, Animal Endothelial cells Endothelial Cells - cytology Endothelial Cells - metabolism Experiments Feet Fetal Blood - cytology Fetal Blood - metabolism Functional magnetic resonance imaging Gene Expression Heart rate Humans Injections, Intra-Arterial Ischemia Laboratory animals Leukocytes (mononuclear) Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - transplantation Male Microvasculature NMR Nuclear magnetic resonance Perfusion Physiology Postural Balance - physiology Rats Rats, Sprague-Dawley Reperfusion Rodents Stem cell transplantation Stem cells Stroke Stroke - metabolism Stroke - pathology Stroke - therapy Transplantation Transplantation, Heterologous Umbilical cord Veins & arteries Von Willebrand factor von Willebrand Factor - genetics von Willebrand Factor - metabolism
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