Sunitinib for the treatment of benign and malignant neoplasms from von Hippel-Lindau disease: A single-arm, prospective phase II clinical study from the PREDIR group

Von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary cancer syndrome that predisposes affected individuals to the development of multiple benign and malignant tumors. One of the main manifestations of VHL is renal cell carcinoma (RCC). RCC is increasingly being treated with targeted t...

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Veröffentlicht in:	Oncotarget 2016-12, Vol.7 (51), p.85306-85317
Hauptverfasser:	Oudard, Stéphane, Elaidi, Reza, Brizard, Mara, Le Rest, Céline, Caillet, Valérie, Deveaux, Sophie, Benoit, Gérard, Corréas, Jean-Michel, Benoudiba, Farida, David, Philippe, Gaudric, Alain, Hammel, Pascal, Joly, Dominique, Timsit, Marc Olivier, Méjean, Arnaud, Richard, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - etiology Carcinoma, Renal Cell - mortality Female France Humans Indoles - therapeutic use Kidney Neoplasms - drug therapy Kidney Neoplasms - etiology Kidney Neoplasms - mortality Male Middle Aged Neoplasm Metastasis Neoplasm Staging Neoplasms - drug therapy Neoplasms - etiology Neoplasms - mortality Prospective Studies Pyrroles - therapeutic use Research Paper Survival Analysis Treatment Outcome von Hippel-Lindau Disease - complications von Hippel-Lindau Disease - drug therapy von Hippel-Lindau Disease - mortality
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