Inhibition of the growth of human melanoma cells by methionine enkephalin

Melanoma is an aggressive cancer, the incidence of which is increasing worldwide. Limited therapies are currently available, particularly following metastasis. The aim of the present study was to investigate the inhibiting effect of methionine enkephalin (MENK) on human melanoma via opioid receptors...

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Veröffentlicht in:	Molecular medicine reports 2016-12, Vol.14 (6), p.5521-5527
Hauptverfasser:	Wang, Dong-Mei, Wang, Guang-Chuan, Yang, Jing, Plotnikoff, Nicolas P, Griffin, Noreen, Han, Yu-Man, Qi, Rui-Qun, Gao, Xing-Hua, Shan, Feng-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Cancer Care and treatment Cell culture Cell cycle Cell Cycle Checkpoints - drug effects Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - drug effects Cells, Cultured Development and progression Enkephalin, Methionine Enkephalin, Methionine - pharmacology Enkephalins G1 phase Gene Expression Health aspects Humans Melanoma Melanoma - metabolism Metastases Methionine methionine encephalin Narcotics Opioid receptors Opioids Pancreatic cancer Phase transitions Polymerase chain reaction Receptors Receptors, Opioid - genetics Receptors, Opioid - metabolism Reverse transcription RNA, Messenger - genetics RNA, Messenger - metabolism Skin cancer Software Studies Survivin
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