A blood-based gene expression and signaling pathway analysis to differentiate between high and low grade gliomas

The aims of the present study were to undertake gene expression profiling of the blood of glioma patients to determine key genetic components of signaling pathways and to develop a panel of genes that could be used as a potential blood-based biomarker to differentiate between high and low grade glio...

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Veröffentlicht in:	Oncology reports 2017-01, Vol.37 (1), p.10-22
Hauptverfasser:	Ponnampalam, Stephen N, Kamaluddin, Nor Rizan, Zakaria, Zubaidah, Matheneswaran, Vickneswaran, Ganesan, Dharmendra, Haspani, Mohammed Saffari, Ryten, Mina, Hardy, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Blood Blood-brain barrier Brain cancer Brain Neoplasms - genetics Brain Neoplasms - pathology Care and treatment Cellular signal transduction Chronic fatigue syndrome Consent Development and progression Disease Female Gender Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic Genetic aspects Glioma Glioma - blood Glioma - genetics Glioma - pathology Gliomas Growth factors Health aspects Histopathology Homeostasis Humans Kinases Male Medical prognosis Medical screening Middle Aged Nervous system NMR Nuclear magnetic resonance Oligonucleotide Array Sequence Analysis - methods Patients Polymerase Chain Reaction - methods Principal Component Analysis Proteins Reproducibility of Results Signal Transduction - genetics Stroke Surgery Transcriptome Tumor necrosis factor-TNF Tumors
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