Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence

This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for ev...

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Veröffentlicht in:BioMed research international 2017-01, Vol.2017 (2017), p.1-5
Hauptverfasser: Nakamura, So, Tsukada, Nobuhiro, Ito, Yujiro, Komatsuda, Akari, Funakoshi, Shinsuke, Sakai, Gen, Nakazawa, Atsushi, Tomita, Masuomi, Maeda, Takahiro, Nagata, Hirohiko
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container_issue 2017
container_start_page 1
container_title BioMed research international
container_volume 2017
creator Nakamura, So
Tsukada, Nobuhiro
Ito, Yujiro
Komatsuda, Akari
Funakoshi, Shinsuke
Sakai, Gen
Nakazawa, Atsushi
Tomita, Masuomi
Maeda, Takahiro
Nagata, Hirohiko
description This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p
doi_str_mv 10.1155/2017/2138073
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The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p&lt;0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2017/2138073</identifier><identifier>PMID: 28337444</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biomedical research ; Bladder ; Cancer therapies ; Care and treatment ; Colorectal cancer ; Constipation ; Constipation - complications ; Constipation - physiopathology ; Cross-Sectional Studies ; Drug therapy ; Family medical history ; Female ; Health aspects ; Hospitals ; Humans ; Laxatives ; Medical research ; Medicine, Experimental ; Middle Aged ; Multivariate analysis ; Prescription drugs ; Quality of life ; Questionnaires ; Severity of Illness Index ; Studies ; Urinary Bladder, Overactive - complications ; Urinary Bladder, Overactive - physiopathology ; Urinary incontinence ; Urinary Incontinence - complications ; Urinary Incontinence - physiopathology ; Urination - physiology ; Urology ; Women patients ; Womens health</subject><ispartof>BioMed research international, 2017-01, Vol.2017 (2017), p.1-5</ispartof><rights>Copyright © 2017 Takahiro Maeda et al.</rights><rights>COPYRIGHT 2017 John Wiley &amp; Sons, Inc.</rights><rights>Copyright © 2017 Takahiro Maeda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2017 Takahiro Maeda et al. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c532t-afb2d9feef0500f00ec7db1c9c91e09c42d999de18bec8e207b500e98a0e86ad3</citedby><cites>FETCH-LOGICAL-c532t-afb2d9feef0500f00ec7db1c9c91e09c42d999de18bec8e207b500e98a0e86ad3</cites><orcidid>0000-0003-4479-7835 ; 0000-0003-2720-7514</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350309/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350309/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28337444$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Chiba, Toshimi</contributor><creatorcontrib>Nakamura, So</creatorcontrib><creatorcontrib>Tsukada, Nobuhiro</creatorcontrib><creatorcontrib>Ito, Yujiro</creatorcontrib><creatorcontrib>Komatsuda, Akari</creatorcontrib><creatorcontrib>Funakoshi, Shinsuke</creatorcontrib><creatorcontrib>Sakai, Gen</creatorcontrib><creatorcontrib>Nakazawa, Atsushi</creatorcontrib><creatorcontrib>Tomita, Masuomi</creatorcontrib><creatorcontrib>Maeda, Takahiro</creatorcontrib><creatorcontrib>Nagata, Hirohiko</creatorcontrib><title>Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. 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The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p&lt;0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>28337444</pmid><doi>10.1155/2017/2138073</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-4479-7835</orcidid><orcidid>https://orcid.org/0000-0003-2720-7514</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Biomedical research
Bladder
Cancer therapies
Care and treatment
Colorectal cancer
Constipation
Constipation - complications
Constipation - physiopathology
Cross-Sectional Studies
Drug therapy
Family medical history
Female
Health aspects
Hospitals
Humans
Laxatives
Medical research
Medicine, Experimental
Middle Aged
Multivariate analysis
Prescription drugs
Quality of life
Questionnaires
Severity of Illness Index
Studies
Urinary Bladder, Overactive - complications
Urinary Bladder, Overactive - physiopathology
Urinary incontinence
Urinary Incontinence - complications
Urinary Incontinence - physiopathology
Urination - physiology
Urology
Women patients
Womens health
title Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence
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