Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence
This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for ev...
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creator | Nakamura, So Tsukada, Nobuhiro Ito, Yujiro Komatsuda, Akari Funakoshi, Shinsuke Sakai, Gen Nakazawa, Atsushi Tomita, Masuomi Maeda, Takahiro Nagata, Hirohiko |
description | This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p |
doi_str_mv | 10.1155/2017/2138073 |
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The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p<0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2017/2138073</identifier><identifier>PMID: 28337444</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biomedical research ; Bladder ; Cancer therapies ; Care and treatment ; Colorectal cancer ; Constipation ; Constipation - complications ; Constipation - physiopathology ; Cross-Sectional Studies ; Drug therapy ; Family medical history ; Female ; Health aspects ; Hospitals ; Humans ; Laxatives ; Medical research ; Medicine, Experimental ; Middle Aged ; Multivariate analysis ; Prescription drugs ; Quality of life ; Questionnaires ; Severity of Illness Index ; Studies ; Urinary Bladder, Overactive - complications ; Urinary Bladder, Overactive - physiopathology ; Urinary incontinence ; Urinary Incontinence - complications ; Urinary Incontinence - physiopathology ; Urination - physiology ; Urology ; Women patients ; Womens health</subject><ispartof>BioMed research international, 2017-01, Vol.2017 (2017), p.1-5</ispartof><rights>Copyright © 2017 Takahiro Maeda et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2017 Takahiro Maeda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2017 Takahiro Maeda et al. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c532t-afb2d9feef0500f00ec7db1c9c91e09c42d999de18bec8e207b500e98a0e86ad3</citedby><cites>FETCH-LOGICAL-c532t-afb2d9feef0500f00ec7db1c9c91e09c42d999de18bec8e207b500e98a0e86ad3</cites><orcidid>0000-0003-4479-7835 ; 0000-0003-2720-7514</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350309/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350309/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28337444$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Chiba, Toshimi</contributor><creatorcontrib>Nakamura, So</creatorcontrib><creatorcontrib>Tsukada, Nobuhiro</creatorcontrib><creatorcontrib>Ito, Yujiro</creatorcontrib><creatorcontrib>Komatsuda, Akari</creatorcontrib><creatorcontrib>Funakoshi, Shinsuke</creatorcontrib><creatorcontrib>Sakai, Gen</creatorcontrib><creatorcontrib>Nakazawa, Atsushi</creatorcontrib><creatorcontrib>Tomita, Masuomi</creatorcontrib><creatorcontrib>Maeda, Takahiro</creatorcontrib><creatorcontrib>Nagata, Hirohiko</creatorcontrib><title>Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p<0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biomedical research</subject><subject>Bladder</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Colorectal cancer</subject><subject>Constipation</subject><subject>Constipation - complications</subject><subject>Constipation - physiopathology</subject><subject>Cross-Sectional Studies</subject><subject>Drug therapy</subject><subject>Family medical history</subject><subject>Female</subject><subject>Health aspects</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Laxatives</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Prescription drugs</subject><subject>Quality of life</subject><subject>Questionnaires</subject><subject>Severity of Illness Index</subject><subject>Studies</subject><subject>Urinary Bladder, Overactive - complications</subject><subject>Urinary Bladder, Overactive - physiopathology</subject><subject>Urinary incontinence</subject><subject>Urinary Incontinence - complications</subject><subject>Urinary Incontinence - physiopathology</subject><subject>Urination - physiology</subject><subject>Urology</subject><subject>Women patients</subject><subject>Womens health</subject><issn>2314-6133</issn><issn>2314-6141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNksFvFCEUxidGY5vam2dD4sVE18IAA1xMthu3btKkB-2ZsPCmSzMDK8xs0_9eJrvdqqdyAfJ--d7H46uq9wR_JYTzixoTcVETKrGgr6rTmhI2awgjr49nSk-q85zvcVmSNFg1b6uTWlIqGGOnVbuE3nSAlmOwg4_BdGgRQx781kxXtMponnO03gzg0IMfNuhmB8kUeAfosjPOQUI_H_vtEPuMTHDoNvlg0iNaBRvD4AMEC--qN63pMpwf9rPqdvn91-LH7PrmarWYX88sp_UwM-26dqoFaDHHuMUYrHBrYpVVBLCyrFSVckDkGqyEGot14UBJg0E2xtGz6ttedzuue3AWwpBMp7fJ98WSjsbrfyvBb_Rd3GlOOaZYFYFPB4EUf4-QB937bKHrTIA4Zk2kIlIwKl-CSlI3gpOmoB__Q-_jmMqwJ0o0TBDZ1M_UXfkR7UMbi0U7ieo554JiwhpeqC97yqaYc4L2-DqC9RQKPYVCH0JR8A9_T-QIP0WgAJ_3wMYHZx78C-VKbEpv80wTyopH-gdRrMjN</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Nakamura, So</creator><creator>Tsukada, Nobuhiro</creator><creator>Ito, Yujiro</creator><creator>Komatsuda, Akari</creator><creator>Funakoshi, Shinsuke</creator><creator>Sakai, Gen</creator><creator>Nakazawa, Atsushi</creator><creator>Tomita, Masuomi</creator><creator>Maeda, Takahiro</creator><creator>Nagata, Hirohiko</creator><general>Hindawi Publishing Corporation</general><general>Hindawi</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4479-7835</orcidid><orcidid>https://orcid.org/0000-0003-2720-7514</orcidid></search><sort><creationdate>20170101</creationdate><title>Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence</title><author>Nakamura, So ; Tsukada, Nobuhiro ; Ito, Yujiro ; Komatsuda, Akari ; Funakoshi, Shinsuke ; Sakai, Gen ; Nakazawa, Atsushi ; Tomita, Masuomi ; Maeda, Takahiro ; Nagata, Hirohiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c532t-afb2d9feef0500f00ec7db1c9c91e09c42d999de18bec8e207b500e98a0e86ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biomedical research</topic><topic>Bladder</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Colorectal cancer</topic><topic>Constipation</topic><topic>Constipation - complications</topic><topic>Constipation - physiopathology</topic><topic>Cross-Sectional Studies</topic><topic>Drug therapy</topic><topic>Family medical history</topic><topic>Female</topic><topic>Health aspects</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Laxatives</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Multivariate analysis</topic><topic>Prescription drugs</topic><topic>Quality of life</topic><topic>Questionnaires</topic><topic>Severity of Illness Index</topic><topic>Studies</topic><topic>Urinary Bladder, Overactive - complications</topic><topic>Urinary Bladder, Overactive - physiopathology</topic><topic>Urinary incontinence</topic><topic>Urinary Incontinence - complications</topic><topic>Urinary Incontinence - physiopathology</topic><topic>Urination - physiology</topic><topic>Urology</topic><topic>Women patients</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakamura, So</creatorcontrib><creatorcontrib>Tsukada, Nobuhiro</creatorcontrib><creatorcontrib>Ito, Yujiro</creatorcontrib><creatorcontrib>Komatsuda, Akari</creatorcontrib><creatorcontrib>Funakoshi, Shinsuke</creatorcontrib><creatorcontrib>Sakai, Gen</creatorcontrib><creatorcontrib>Nakazawa, Atsushi</creatorcontrib><creatorcontrib>Tomita, Masuomi</creatorcontrib><creatorcontrib>Maeda, Takahiro</creatorcontrib><creatorcontrib>Nagata, Hirohiko</creatorcontrib><collection>الدوريات العلمية والإحصائية - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BioMed research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamura, So</au><au>Tsukada, Nobuhiro</au><au>Ito, Yujiro</au><au>Komatsuda, Akari</au><au>Funakoshi, Shinsuke</au><au>Sakai, Gen</au><au>Nakazawa, Atsushi</au><au>Tomita, Masuomi</au><au>Maeda, Takahiro</au><au>Nagata, Hirohiko</au><au>Chiba, Toshimi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>2017</volume><issue>2017</issue><spage>1</spage><epage>5</epage><pages>1-5</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p<0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>28337444</pmid><doi>10.1155/2017/2138073</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-4479-7835</orcidid><orcidid>https://orcid.org/0000-0003-2720-7514</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Biomedical research Bladder Cancer therapies Care and treatment Colorectal cancer Constipation Constipation - complications Constipation - physiopathology Cross-Sectional Studies Drug therapy Family medical history Female Health aspects Hospitals Humans Laxatives Medical research Medicine, Experimental Middle Aged Multivariate analysis Prescription drugs Quality of life Questionnaires Severity of Illness Index Studies Urinary Bladder, Overactive - complications Urinary Bladder, Overactive - physiopathology Urinary incontinence Urinary Incontinence - complications Urinary Incontinence - physiopathology Urination - physiology Urology Women patients Womens health |
title | Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence |
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