Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and necrosis and results from iron‐dependent lipid peroxide accumulation. Ferroptotic cell death is characterized by cytological changes, including cell volume shrinkage and increased mitochondrial membrane...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2017-04, Vol.21 (4), p.648-657
Hauptverfasser:	Yu, Haitao, Guo, Pengyi, Xie, Xiaozai, Wang, Yi, Chen, Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Artemisinin Autophagy Cell death Cell proliferation Cell size Chemical compounds erastin Ferroptosis Glutathione peroxidase Hepatocellular carcinoma Humans Inhibitors Iron Iron - metabolism iron‐dependent cell death Kidney cancer Lipids Liver cancer Metabolic Networks and Pathways Mevalonic acid Mitochondria Models, Biological Morphology Necrosis Neoplasms - pathology Ovarian cancer Oxidation Pancreas Pancreatic cancer Pancreatic carcinoma Peroxide Renal cell carcinoma Review Reviews Sulfur Tumors tumourous diseases
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