Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications

Acetate, together with other short chain fatty acids has been implicated in colorectal cancer (CRC) prevention/therapy. Acetate was shown to induce apoptosis in CRC cells. The precise mechanism underlying acetate transport across CRC cells membrane, that may be implicated in its selectivity towards...

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Veröffentlicht in:	Oncotarget 2016-10, Vol.7 (43), p.70639-70653
Hauptverfasser:	Ferro, Suellen, Azevedo-Silva, João, Casal, Margarida, Côrte-Real, Manuela, Baltazar, Fatima, Preto, Ana
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - metabolism Biological Transport Cell Line, Tumor Colorectal Neoplasms - drug therapy Colorectal Neoplasms - metabolism Glycolysis Humans Monocarboxylic Acid Transporters - genetics Muscle Proteins - genetics Pyruvates - pharmacology Pyruvates - therapeutic use Research Paper Symporters - genetics
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