Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib

We evalueted a systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) with the aim to explored their prognostic value in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib. 56 advanced HCC patients receiving sorafe...

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Veröffentlicht in:	Oncotarget 2016-10, Vol.7 (41), p.67142-67149
Hauptverfasser:	Casadei Gardini, Andrea, Scarpi, Emanuela, Faloppi, Luca, Scartozzi, Mario, Silvestris, Nicola, Santini, Daniele, de Stefano, Giorgio, Marisi, Giorgia, Negri, Francesca V, Foschi, Francesco Giuseppe, Valgiusti, Martina, Ercolani, Giorgio, Frassineti, Giovanni Luca
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - therapeutic use Biomarkers, Tumor - immunology Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - mortality Disease-Free Survival Female Humans Inflammation - immunology Kaplan-Meier Estimate Liver Neoplasms - drug therapy Liver Neoplasms - immunology Liver Neoplasms - mortality Male Middle Aged Niacinamide - analogs & derivatives Niacinamide - therapeutic use Phenylurea Compounds - therapeutic use Prognosis Proportional Hazards Models Research Paper Retrospective Studies
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