Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration

Urothelium is the protective lining of the urinary tract. The mechanisms underlying urothelial formation and maintenance are largely unknown. Here, we report the stage-specific roles of PRC2 epigenetic regulators in embryonic and adult urothelial progenitors. Without Eed, the obligatory subunit of P...

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