Modulations of SIR-nucleosome interactions of reconstructed yeast silent pre-heterochromatin by O-acetyl-ADP-ribose and magnesium

Yeast silent heterochromatin provides an excellent model with which to study epigenetic inheritance. Previously we developed an in vitro assembly system to demonstrate the formation of filament structures with requirements that mirror yeast epigenetic gene silencing in vivo. However, the properties...

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Veröffentlicht in:	Molecular biology of the cell 2017-02, Vol.28 (3), p.381-386
Hauptverfasser:	Tung, Shu-Yun, Wang, Sue-Hong, Lee, Sue-Ping, Tsai, Shu-Ping, Shen, Hsiao-Hsuian, Chen, Feng-Jung, Wu, Yu-Yi, Hsiao, Sheng-Pin, Liou, Gunn-Guang
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Brief Reports Chromatin - metabolism Chromatin Assembly and Disassembly Epigenomics - methods Gene Silencing - physiology Heterochromatin - metabolism Histones - metabolism Magnesium Nucleosomes - metabolism O-Acetyl-ADP-Ribose - metabolism Protein Processing, Post-Translational Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism Sirtuins - metabolism Telomere - metabolism
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