A network-based method for mechanistic investigation of Shexiang Baoxin Pill’s treatment of cardiovascular diseases

Shexiang Baoxin Pill (SBP), a traditional Chinese medicine formula, is commonly used to treat cardiovascular disease (CVD) in China. However, the complexity of composition and targets has deterred our understanding of its mechanism of action. Using network pharmacology-based approaches, we establish...

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Veröffentlicht in:	Scientific reports 2017-03, Vol.7 (1), p.43632-43632, Article 43632
Hauptverfasser:	Fang, Hai-Yang, Zeng, Hua-Wu, Lin, Li-Mei, Chen, Xing, Shen, Xiao-Na, Fu, Peng, Lv, Chao, Liu, Qun, Liu, Run-Hui, Zhang, Wei-Dong, Zhao, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	38/39 631/114/2408 631/154/436 Cardiovascular diseases Cardiovascular Diseases - drug therapy Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Cell Line Chinese medicine Computer applications DNA microarrays Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Gene expression Gene Expression Regulation - drug effects Gene Regulatory Networks Humanities and Social Sciences Humans multidisciplinary Protein interaction Protein Interaction Mapping Protein Interaction Maps Proteins Reproducibility of Results Science Signal Transduction Traditional Chinese medicine
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