Hotspots of MLV integration in the hematopoietic tumor genome

Extensive research has been performed regarding the integration sites of murine leukemia retrovirus (MLV) for the identification of proto-oncogenes. To date, the overlap of mutations within specific oligonucleotides across different tumor genomes has been regarded as a rare event; however, a recent...

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Veröffentlicht in:	Oncogene 2017-03, Vol.36 (9), p.1169-1175
Hauptverfasser:	Tsuruyama, T, Hiratsuka, T, Yamada, N
Format:	Artikel
Sprache:	eng
Schlagworte:	45/77 631/208/68 631/67/1858 64 64/60 Apoptosis Cell Biology Development and progression Gene mutation Genetic aspects Genome, Human Genomes Health aspects Hematologic Neoplasms - genetics Human Genetics Humans Internal Medicine Leukemia Leukemia Virus, Murine - genetics Medical research Medicine Medicine & Public Health Myeloproliferative disorders Oncogenes Oncology Retroviridae Review Virus Integration - genetics Viruses
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