Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs

Positive affect denotes a state of pleasurable engagement with the environment eliciting positive emotion such as contentment, enthusiasm or happiness. Positive affect is associated with favorable psychological, physical and economic outcomes in many longitudinal studies. With a heritability of ⩽64%...

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Veröffentlicht in:	Molecular psychiatry 2017-05, Vol.22 (5), p.774-783
Hauptverfasser:	Wingo, A P, Almli, L M, Stevens, J S, Jovanovic, T, Wingo, T S, Tharp, G, Li, Y, Lori, A, Briscione, M, Jin, P, Binder, E B, Bradley, B, Gibson, G, Ressler, K J
Format:	Artikel
Sprache:	eng
Schlagworte:	38/43 631/208 631/337 631/378 Adult African Americans Alleles Behavioral Sciences Biological Psychology Black or African American - genetics Chromosomes, Human, Pair 1 Emotions Emotions - physiology Female Gene Frequency Genetic diversity Genetic factors Genetic Variation Genome-wide association studies Genome-Wide Association Study - methods Genomes Happiness Heritability Humans Introns Longitudinal studies Male Medicine Medicine & Public Health MicroRNAs MicroRNAs - biosynthesis MicroRNAs - genetics Middle Aged miRNA Neurosciences Nucleus accumbens original-article Pharmacotherapy Pleasure - physiology Polymorphism Polymorphism, Single Nucleotide Psychiatry Reinforcement Single-nucleotide polymorphism
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