Lactobacillus rhamnosus GG supernatant enhance neonatal resistance to systemic Escherichia coli K1 infection by accelerating development of intestinal defense

The objective of this study was to determine whether Lactobacillus rhamnosus GG culture supernatant (LCS) has a preventive effect against gut-derived systemic neonatal Escherichia coli (E. coli ) K1 infection. The preventive effects were evaluated in human colonic carcinoma cell line Caco-2 and neon...

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Veröffentlicht in:	Scientific reports 2017-03, Vol.7 (1), p.43305, Article 43305
Hauptverfasser:	He, Xiaolong, Zeng, Qing, Puthiyakunnon, Santhosh, Zeng, Zhijie, Yang, Weijun, Qiu, Jiawen, Du, Lei, Boddu, Swapna, Wu, Tongwei, Cai, Danxian, Huang, Sheng-He, Cao, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/106 631/250/255/1318 631/326/421 692/420/254 Animal models Cell culture Colonization E coli Escherichia coli Gastrointestinal tract Humanities and Social Sciences Immunoglobulin A Infections Intestine Mucin multidisciplinary Neonates Permeability Rodents Science Translocation Zonula occludens-1 protein
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