Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction

Genome-wide association studies (GWAS) have identified more than sixty single nucleotide polymorphisms (SNPs) associated with increased risk for type 2 diabetes (T2D). However, the identification of causal risk SNPs for T2D pathogenesis was complicated by the factor that each risk SNP is a surrogate...

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Veröffentlicht in:	Scientific reports 2017-03, Vol.7 (1), p.43709-43709, Article 43709
Hauptverfasser:	Wu, Yiming, Jing, Runyu, Dong, Yongcheng, Kuang, Qifan, Li, Yan, Huang, Ziyan, Gan, Wei, Xue, Yue, Li, Yizhou, Li, Menglong
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/1305 631/114/2404 Diabetes Diabetes mellitus Genome-wide association studies Genomes Health risks Humanities and Social Sciences multidisciplinary Pancreas Polymorphism Reclassification Science Single-nucleotide polymorphism Transcription factors
Online-Zugang:	Volltext
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