Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata

The anterior pericardial wall of the snail Biomphalaria glabrata has been identified as a site of hemocyte production, hence has been named the amebocyte-producing organ (APO). A number of studies have shown that exogenous abiotic and biotic substances, including pathogen associated molecular patter...

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Veröffentlicht in:	Developmental and comparative immunology 2016-03, Vol.56, p.25-36
Hauptverfasser:	Zhang, Si-Ming, Loker, Eric S., Sullivan, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amebocyte-producing organ (APO) aminoacyl tRNA ligases Aminoacyl-tRNA synthetase Animals arginase Biomphalaria - anatomy & histology Biomphalaria - genetics Biomphalaria - immunology Biomphalaria - microbiology Biomphalaria glabrata calmodulin Cell Proliferation cytochrome P-450 fucoidan Gene Expression gene expression regulation genes GiMAP glutathione transferase guanosinetriphosphatase hemocytes immune response Immunity, Innate innate immunity lipopolysaccharides Lipopolysaccharides - metabolism microarray technology mitosis Mollusk multiple drug resistance Pathogen associated molecular pattern (PAMP) Pathogen-Associated Molecular Pattern Molecules - chemistry Pathogen-Associated Molecular Pattern Molecules - immunology Pathogen-Associated Molecular Pattern Molecules - metabolism pathogens peptidoglycans pericardium permeability protein synthesis RNA Schistosoma mansoni snails transcriptomics tumor necrosis factors ubiquitin-protein ligase
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