Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats

Abstract Cathinone and many of its analogs produce behavioral effects by promoting transporter-mediated release of the monoamine neurotransmitters dopamine, norepinephrine and/or serotonin. Stereoselectivity is one determinant of neurochemical and behavioral effects of cathinone analogs. This study...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European neuropsychopharmacology 2016-02, Vol.26 (2), p.288-297
Hauptverfasser:	Hutsell, Blake A, Baumann, Michael H, Partilla, John S, Banks, Matthew L, Vekariya, Rakesh, Glennon, Richard A, Negus, S. Stevens
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Methylcathinone Alkaloids - adverse effects Alkaloids - chemistry Analysis of Variance Animals Cathinone Central Nervous System Stimulants - adverse effects Central Nervous System Stimulants - chemistry Disease Models, Animal Dopamine Plasma Membrane Transport Proteins - metabolism Dose-Response Relationship, Drug Drug abuse In Vitro Techniques Internal Medicine Intracranial self-stimulation Male Psychiatry Rat Rats Rats, Sprague-Dawley Self Stimulation Serotonin Plasma Membrane Transport Proteins - metabolism Stereoisomerism Stereoselectivity Substance-Related Disorders - metabolism Substance-Related Disorders - physiopathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!