TGR5 expression in benign, preneoplastic and neoplastic lesions of Barrett’s esophagus: Case series and findings

AIM To examined the bile acid receptor TGR5 expression in squamous mucosa, Barrett’s mucosa, dysplasia and esophageal adenocarcinoma(EA). METHODS Slides were stained with TGR5 antibody. The staining intensity was scored as 1+, 2+ and 3+. The extent of staining(percentage of cells staining) was score...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2017-02, Vol.23 (8), p.1338-1344
Hauptverfasser:	Marketkar, Shivali, Li, Dan, Yang, Dongfang, Cao, Weibiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Aged Aged, 80 and over Barrett Esophagus - genetics Barrett Esophagus - metabolism Basic Study Bile Acids and Salts - chemistry Cell Line, Tumor Disease Progression Esophageal Neoplasms - genetics Esophageal Neoplasms - metabolism Female Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Lymphatic Metastasis Male Middle Aged Prognosis Real-Time Polymerase Chain Reaction Receptors, G-Protein-Coupled - metabolism
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