Nanocarriers for vascular delivery of anti-inflammatory agents

There is a need for improved treatment of acute vascular inflammation in conditions such as ischemia-reperfusion injury, acute lung injury, sepsis, and stroke. The vascular endothelium represents an important therapeutic target in these conditions. Furthermore, some anti-inflammatory agents (AIAs) (...

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Veröffentlicht in:	Annual review of pharmacology and toxicology 2014-01, Vol.54 (1), p.205-226
Hauptverfasser:	Howard, Melissa D, Hood, Elizabeth D, Zern, Blaine, Shuvaev, Vladimir V, Grosser, Tilo, Muzykantov, Vladimir R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Disease Models, Animal Drug Delivery Systems - methods Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Humans Inflammation - drug therapy Nanostructures - chemistry Vascular Diseases - drug therapy
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