Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

Nuclear factor erythroid-2-related factor 2 (Nrf2), a master transcription factor in the antioxidant response, has been found to be ubiquitously expressed in various cancer cells and in the regulation tumor proliferation, invasion, and chemoresistance activities. The regulatory roles of Nrf2 in cont...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncotarget 2016-10, Vol.7 (40), p.65389-65402
Hauptverfasser:	Liu, Danyang, Zhang, Yonglong, Wei, Yingze, Liu, Guoyuan, Liu, Yufeng, Gao, Qiongmei, Zou, Liping, Zeng, Wenjiao, Zhang, Nong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinogenesis - metabolism Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Cell Cycle Cell Proliferation Feedback, Physiological Follow-Up Studies Hep G2 Cells Humans Liver Neoplasms - metabolism Liver Neoplasms - mortality Liver Neoplasms - pathology Male Mice Mice, Inbred BALB C Mice, Nude NF-E2-Related Factor 2 - metabolism Platelet-Derived Growth Factor - metabolism Proto-Oncogene Proteins c-akt - metabolism Research Paper Signal Transduction Survival Analysis Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!