Development of oseltamivir and zanamivir resistance in influenza A(H1N1)pdm09 virus, Denmark, 2014

Antiviral treatment of immunocompromised patients with prolonged influenza virus infection can lead to multidrug resistance. This study reveals the selection of antiviral resistance mutations in influenza A(H1N1)pdm09 virus in an immunocompromised patient during a 6-month period. The patient was tre...

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Veröffentlicht in:	Euro surveillance : bulletin européen sur les maladies transmissibles 2017-01, Vol.22 (3), p.1
Hauptverfasser:	Trebbien, Ramona, Pedersen, Svend Stenvang, Vorborg, Kristine, Franck, Kristina Træholt, Fischer, Thea Kølsen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral drugs Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Denmark Drug resistance Drug Resistance, Viral - genetics Genotype Humans Immunocompromised Host Influenza A Virus, H1N1 Subtype - drug effects Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - isolation & purification Influenza, Human - diagnosis Influenza, Human - drug therapy Influenza, Human - virology Leukemia, Lymphocytic, Chronic, B-Cell - complications Medical treatment Middle Aged Mutation Mutation - drug effects Neuraminidase - genetics Oseltamivir - pharmacology Reverse Transcriptase Polymerase Chain Reaction Treatment Outcome Zanamivir - pharmacology
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