CR-LAAO, an L-amino acid oxidase from Calloselasma rhodostoma venom, as a potential tool for developing novel immunotherapeutic strategies against cancer

L-amino acid oxidases from snake venoms have been described to possess various biological functions. In this study, we investigated the inflammatory responses induced in vivo and in vitro by CR-LAAO, an L-amino acid oxidase isolated from Calloselasma rhodostoma venom, and its antitumor potential. CR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2017-02, Vol.7 (1), p.42673, Article 42673
Hauptverfasser:	Costa, Tássia R., Menaldo, Danilo L., Zoccal, Karina F., Burin, Sandra M., Aissa, Alexandre F., Castro, Fabíola A. de, Faccioli, Lúcia H., Greggi Antunes, Lusânia M., Sampaio, Suely V.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 13/31 38/77 38/90 631/250/256/2516 631/67/580 82/80 Amino acid oxidase Amino acids Apoptosis Cancer Caspase Caspase-8 Cell activation Cell cycle Humanities and Social Sciences Hydrogen peroxide Inflammation Interleukin 6 Leukocytes (neutrophilic) Macrophages multidisciplinary Oxidative stress Peritoneum Prostaglandin E2 Science TLR2 protein TLR4 protein Toll-like receptors Toxins Tumor cells Venom
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!