On the Mechanics of Transcatheter Aortic Valve Replacement
Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve technology. TAVs are truly transformational as they bring the benefit of heart valve replacement to patients that would otherwise not be operated on. Nevertheless, like any new device technology, the high expe...
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| Veröffentlicht in: | Annals of biomedical engineering 2017-02, Vol.45 (2), p.310-331 |
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| creator | Dasi, Lakshmi P. Hatoum, Hoda Kheradvar, Arash Zareian, Ramin Alavi, S. Hamed Sun, Wei Martin, Caitlin Pham, Thuy Wang, Qian Midha, Prem A. Raghav, Vrishank Yoganathan, Ajit P. |
| description | Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve technology. TAVs are truly transformational as they bring the benefit of heart valve replacement to patients that would otherwise not be operated on. Nevertheless, like any new device technology, the high expectations are dampened with growing concerns arising from frequent complications that develop in patients, indicating that the technology is far from being mature. Some of the most common complications that plague current TAV devices include malpositioning, crimp-induced leaflet damage, paravalvular leak, thrombosis, conduction abnormalities and prosthesis-patient mismatch. In this article, we provide an in-depth review of the current state-of-the-art pertaining the mechanics of TAVs while highlighting various studies guiding clinicians, regulatory agencies, and next-generation device designers. |
| doi_str_mv | 10.1007/s10439-016-1759-3 |
| format | Article |
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Some of the most common complications that plague current TAV devices include malpositioning, crimp-induced leaflet damage, paravalvular leak, thrombosis, conduction abnormalities and prosthesis-patient mismatch. In this article, we provide an in-depth review of the current state-of-the-art pertaining the mechanics of TAVs while highlighting various studies guiding clinicians, regulatory agencies, and next-generation device designers.</description><identifier>ISSN: 0090-6964</identifier><identifier>EISSN: 1573-9686</identifier><identifier>DOI: 10.1007/s10439-016-1759-3</identifier><identifier>PMID: 27873034</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Abnormalities ; Animals ; Biochemistry ; Biological and Medical Physics ; Biomedical and Life Sciences ; Biomedical Engineering and Bioengineering ; Biomedicine ; Biophysics ; Classical Mechanics ; Devices ; Heart Valve Prosthesis ; Heart valves ; Humans ; Patients ; Prosthesis Design - methods ; Prosthetics ; Regulatory agencies ; State of the art ; The Pursuit of Engineering the Ideal Heart Valve Replacement or Repair ; Thromboembolism ; Transcatheter Aortic Valve Replacement - adverse effects ; Transcatheter Aortic Valve Replacement - instrumentation ; Transcatheter Aortic Valve Replacement - methods ; Valves</subject><ispartof>Annals of biomedical engineering, 2017-02, Vol.45 (2), p.310-331</ispartof><rights>Biomedical Engineering Society 2016</rights><rights>Annals of Biomedical Engineering is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c536t-3f0cf4fd52d62203aa74ac19092216b1036810a86b9acdbc957db829e111d3bc3</citedby><cites>FETCH-LOGICAL-c536t-3f0cf4fd52d62203aa74ac19092216b1036810a86b9acdbc957db829e111d3bc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10439-016-1759-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10439-016-1759-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27873034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dasi, Lakshmi P.</creatorcontrib><creatorcontrib>Hatoum, Hoda</creatorcontrib><creatorcontrib>Kheradvar, Arash</creatorcontrib><creatorcontrib>Zareian, Ramin</creatorcontrib><creatorcontrib>Alavi, S. Hamed</creatorcontrib><creatorcontrib>Sun, Wei</creatorcontrib><creatorcontrib>Martin, Caitlin</creatorcontrib><creatorcontrib>Pham, Thuy</creatorcontrib><creatorcontrib>Wang, Qian</creatorcontrib><creatorcontrib>Midha, Prem A.</creatorcontrib><creatorcontrib>Raghav, Vrishank</creatorcontrib><creatorcontrib>Yoganathan, Ajit P.</creatorcontrib><title>On the Mechanics of Transcatheter Aortic Valve Replacement</title><title>Annals of biomedical engineering</title><addtitle>Ann Biomed Eng</addtitle><addtitle>Ann Biomed Eng</addtitle><description>Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve technology. TAVs are truly transformational as they bring the benefit of heart valve replacement to patients that would otherwise not be operated on. Nevertheless, like any new device technology, the high expectations are dampened with growing concerns arising from frequent complications that develop in patients, indicating that the technology is far from being mature. Some of the most common complications that plague current TAV devices include malpositioning, crimp-induced leaflet damage, paravalvular leak, thrombosis, conduction abnormalities and prosthesis-patient mismatch. 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Hamed</au><au>Sun, Wei</au><au>Martin, Caitlin</au><au>Pham, Thuy</au><au>Wang, Qian</au><au>Midha, Prem A.</au><au>Raghav, Vrishank</au><au>Yoganathan, Ajit P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>On the Mechanics of Transcatheter Aortic Valve Replacement</atitle><jtitle>Annals of biomedical engineering</jtitle><stitle>Ann Biomed Eng</stitle><addtitle>Ann Biomed Eng</addtitle><date>2017-02-01</date><risdate>2017</risdate><volume>45</volume><issue>2</issue><spage>310</spage><epage>331</epage><pages>310-331</pages><issn>0090-6964</issn><eissn>1573-9686</eissn><abstract>Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve technology. TAVs are truly transformational as they bring the benefit of heart valve replacement to patients that would otherwise not be operated on. Nevertheless, like any new device technology, the high expectations are dampened with growing concerns arising from frequent complications that develop in patients, indicating that the technology is far from being mature. Some of the most common complications that plague current TAV devices include malpositioning, crimp-induced leaflet damage, paravalvular leak, thrombosis, conduction abnormalities and prosthesis-patient mismatch. In this article, we provide an in-depth review of the current state-of-the-art pertaining the mechanics of TAVs while highlighting various studies guiding clinicians, regulatory agencies, and next-generation device designers.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>27873034</pmid><doi>10.1007/s10439-016-1759-3</doi><tpages>22</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Abnormalities Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Biophysics Classical Mechanics Devices Heart Valve Prosthesis Heart valves Humans Patients Prosthesis Design - methods Prosthetics Regulatory agencies State of the art The Pursuit of Engineering the Ideal Heart Valve Replacement or Repair Thromboembolism Transcatheter Aortic Valve Replacement - adverse effects Transcatheter Aortic Valve Replacement - instrumentation Transcatheter Aortic Valve Replacement - methods Valves |
| title | On the Mechanics of Transcatheter Aortic Valve Replacement |
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