6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice

The anti-diabetic activity of ginger powder ( ) has been recently promoted, with the recommendation to be included as one of the dietary supplements for diabetic patients. However, previous studies presented different results, which may be caused by degradation and metabolic changes of ginger compon...

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Veröffentlicht in:	International journal of molecular sciences 2017-01, Vol.18 (1), p.168-168
Hauptverfasser:	Wei, Chien-Kei, Tsai, Yi-Hong, Korinek, Michal, Hung, Pei-Hsuan, El-Shazly, Mohamed, Cheng, Yuan-Bin, Wu, Yang-Chang, Hsieh, Tusty-Jiuan, Chang, Fang-Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adenosine kinase Adenosine monophosphate Adipocytes Adipocytes - cytology Adipocytes - drug effects Adipocytes - metabolism AMP-Activated Protein Kinases - metabolism Animals Blood Glucose - metabolism Body weight Catechols - pharmacology Cell Line Cholesterol Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - etiology Diet, High-Fat - adverse effects Ginger Glucose Glucose - metabolism Glucose Tolerance Test Guaiacol - analogs & derivatives Guaiacol - pharmacology High fat diet Humans Hyperglycemia - blood Hyperglycemia - etiology Immunoblotting Ketones - pharmacology Kinases Lipids - biosynthesis Male Mice Mice, Inbred C57BL Muscle Fibers, Skeletal - cytology Muscle Fibers, Skeletal - drug effects Muscle Fibers, Skeletal - metabolism Myotubes Phosphorylation Phosphorylation - drug effects Phytotherapy - methods Powder Protein kinase Pungent principles Shogaols Weight reduction Zingerone Zingiber officinale Zingiber officinale - chemistry
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