Shrimp AHPND-causing plasmids encoding the PirAB toxins as mediated by pirAB-Tn903 are prevalent in various Vibrio species

Shrimp AHPND-causing plasmids encoding the PirAB toxins as mediated by pirAB-Tn903 are prevalent in various Vibrio species

Acute hepatopancreatic necrosis disease (AHPND) is a newly emerging shrimp disease caused by pirAB toxins encoded by a plasmid found in Vibrio parahaemolyticus . The pirAB toxins are the homologs of the Photorhabdus insect-related (Pir) toxins. Here, we report the complete sequences of the AHPND-cau...

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Veröffentlicht in:Scientific reports 2017-02, Vol.7 (1), p.42177-42177, Article 42177
Hauptverfasser: Xiao, Jinzhou, Liu, Liyuan, Ke, Yiyun, Li, Xiefei, Liu, Yunfei, Pan, Yingjie, Yan, Shuling, Wang, Yongjie
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container_issue 1
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container_title Scientific reports
container_volume 7
creator Xiao, Jinzhou
Liu, Liyuan
Ke, Yiyun
Li, Xiefei
Liu, Yunfei
Pan, Yingjie
Yan, Shuling
Wang, Yongjie
description Acute hepatopancreatic necrosis disease (AHPND) is a newly emerging shrimp disease caused by pirAB toxins encoded by a plasmid found in Vibrio parahaemolyticus . The pirAB toxins are the homologs of the Photorhabdus insect-related (Pir) toxins. Here, we report the complete sequences of the AHPND-causing plasmid isolated from V. owensii , as well as those of its 11 siblings (pVH family). In addition, we also included 13 related plasmids (pVH-r family) without the pirAB genes isolated from a variety of species within the Vibrio Harveyi clade. Furthermore, the pirAB -Tn903 composite transposon was identified in pVH, and both ends of the transposon appeared to have inserted simultaneously into the ancestor plasmid at different sites. The homologue counterparts of pirAB were also detected in a non-pVH plasmid in V. campbellii . Taken together, our results provide novel insights into the acquisition and evolution of pirAB as well as related plasmids in the Vibrio Harveyi clade.
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subjects 45
45/44
631/114/2164
631/326/41
Humanities and Social Sciences
multidisciplinary
Plasmids
Science
Siblings
Transposons
title Shrimp AHPND-causing plasmids encoding the PirAB toxins as mediated by pirAB-Tn903 are prevalent in various Vibrio species
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