Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome

The metabolic syndrome (MetS) is a constellation of metabolic disorders that increase the risk of developing several diseases including type 2 diabetes and cardiovascular diseases. Although genome-wide association studies (GWAS) have successfully identified variants associated with individual traits...

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Veröffentlicht in:	Molecular genetics and metabolism 2015-12, Vol.116 (4), p.305-313
Hauptverfasser:	Tekola-Ayele, Fasil, Doumatey, Ayo P., Shriner, Daniel, Bentley, Amy R., Chen, Guanjie, Zhou, Jie, Fasanmade, Olufemi, Johnson, Thomas, Oli, Johnnie, Okafor, Godfrey, Eghan, Benjami A., Agyenim-Boateng, Kofi, Adebamowo, Clement, Amoah, Albert, Acheampong, Joseph, Adeyemo, Adebowale, Rotimi, Charles N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African ancestry alpha Catenin - genetics Black or African American Black People Blood Pressure Cholesterol Ester Transfer Proteins - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study Ghana Heterogeneous-Nuclear Ribonucleoprotein Group C - genetics Humans Kenya Lipoprotein Lipase - genetics Male Metabolic syndrome Metabolic Syndrome - diagnosis Metabolic Syndrome - ethnology Metabolic Syndrome - genetics Metabolic Syndrome - pathology Middle Aged Nerve Tissue Proteins - genetics Nigeria Phenotype Pleiotropy Polymorphism, Single Nucleotide Protein Serine-Threonine Kinases - genetics Triglycerides - blood White People
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