Guiding Neuronal Development with in situ Microfabrication

We report the ability to modify microscopic 3D topographies within dissociated cultures, providing a means to alter the development of neurons as they extend neurites and establish interconnections. In this approach, multiphoton excitation is used to focally excite noncytotoxic photosensitizers that...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-11, Vol.101 (46), p.16104-16108
Hauptverfasser:	Kaehr, Bryan, Allen, Richard, Javier, David J., Currie, John, Shear, Jason B., Hackerman, Norman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological Sciences Cattle Cell Culture Techniques Cell Differentiation Cell growth Cell lines Cells, Cultured Chemistry Cross-Linking Reagents Crosslinking Lasers Mice Micrometers Microscopy Microscopy, Electron, Scanning Microstructure Nanostructures Neurites Neurons Neurons - cytology Photosensitizing agents Physical Sciences Proteins Rats Serum Albumin, Bovine Wavelengths
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