Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature
We report a rare case of pancreatic carcinosarcoma involving a 44-year-old woman. The patient complained of discomfort associated with the upper abdomen and jaundice of skin and sclera for 1 week. After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of...
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| Veröffentlicht in: | Medicine (Baltimore) 2017-01, Vol.96 (4), p.e5966-e5966 |
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| creator | Jia, Zhe Zhang, Ke Huang, RongHai Zhou, XinGang Jiang, Li |
| description | We report a rare case of pancreatic carcinosarcoma involving a 44-year-old woman. The patient complained of discomfort associated with the upper abdomen and jaundice of skin and sclera for 1 week.
After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of the pancreatic head.
Whipple procedure was conducted in May 2013. Intraoperative exploration indicated 2 components of the tumor: a fish-shaped gray matter and a hard structure similar to cancellous bone. Histopathological examination showed adenocarcinoma and osteosarcoma. After surgery, the patient received 8 cycles of chemotherapy with gemcitabine and raltitrexed.
Previous studies indicated poor prognosis for pancreatic carcinosarcoma. However, our patient survived for 31 months with no recurrence till date.
Coexistence of pancreatic adenocarcinoma and osteosarcoma is very rare. Our case was also an exception in manifesting longer survival than expected. |
| doi_str_mv | 10.1097/MD.0000000000005966 |
| format | Article |
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After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of the pancreatic head.
Whipple procedure was conducted in May 2013. Intraoperative exploration indicated 2 components of the tumor: a fish-shaped gray matter and a hard structure similar to cancellous bone. Histopathological examination showed adenocarcinoma and osteosarcoma. After surgery, the patient received 8 cycles of chemotherapy with gemcitabine and raltitrexed.
Previous studies indicated poor prognosis for pancreatic carcinosarcoma. However, our patient survived for 31 months with no recurrence till date.
Coexistence of pancreatic adenocarcinoma and osteosarcoma is very rare. Our case was also an exception in manifesting longer survival than expected.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000005966</identifier><identifier>PMID: 28121946</identifier><language>eng</language><publisher>United States: The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Adult ; Carcinosarcoma - pathology ; Carcinosarcoma - therapy ; Clinical Case Report ; Female ; Humans ; Pancreas - pathology ; Pancreatic Neoplasms - pathology ; Pancreatic Neoplasms - therapy</subject><ispartof>Medicine (Baltimore), 2017-01, Vol.96 (4), p.e5966-e5966</ispartof><rights>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><rights>Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3555-83fa854b2303790d379cca387ad1d01ca818cbadca494ef51c3448f859c4640c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287970/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287970/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28121946$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jia, Zhe</creatorcontrib><creatorcontrib>Zhang, Ke</creatorcontrib><creatorcontrib>Huang, RongHai</creatorcontrib><creatorcontrib>Zhou, XinGang</creatorcontrib><creatorcontrib>Jiang, Li</creatorcontrib><title>Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>We report a rare case of pancreatic carcinosarcoma involving a 44-year-old woman. The patient complained of discomfort associated with the upper abdomen and jaundice of skin and sclera for 1 week.
After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of the pancreatic head.
Whipple procedure was conducted in May 2013. Intraoperative exploration indicated 2 components of the tumor: a fish-shaped gray matter and a hard structure similar to cancellous bone. Histopathological examination showed adenocarcinoma and osteosarcoma. After surgery, the patient received 8 cycles of chemotherapy with gemcitabine and raltitrexed.
Previous studies indicated poor prognosis for pancreatic carcinosarcoma. However, our patient survived for 31 months with no recurrence till date.
Coexistence of pancreatic adenocarcinoma and osteosarcoma is very rare. Our case was also an exception in manifesting longer survival than expected.</description><subject>Adult</subject><subject>Carcinosarcoma - pathology</subject><subject>Carcinosarcoma - therapy</subject><subject>Clinical Case Report</subject><subject>Female</subject><subject>Humans</subject><subject>Pancreas - pathology</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Pancreatic Neoplasms - therapy</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV1vFCEUhomxsWv1F5gYLr2Zls8BvDAxWz-atGkv9BrPMkwHnRlWYHbjvxfdtqlywTmB530h50XoFSWnlBh1dnV-Sh4tadr2CVpRydum9uIpWhHCZKOMEsfoec7fCaFcMfEMHTNNGTWiXaFvNzC75KEEhx0kF-aYa4kT4H0oA06QPB7jfNsUnyacl7QLOxjf4jVkj5PfxlQwzF1td8HvcexxGaoiVBzKkvwLdNTDmP3Lu3qCvn788GX9ubm8_nSxfn_ZOC6lbDTvQUuxYZxwZUhXN-eAawUd7Qh1oKl2G-gcCCN8L6njQuheS-NEK4jjJ-jdwXe7bCbfOT-XBKPdpjBB-mUjBPvvzRwGext3VjJdR0SqwZs7gxR_Lj4XO4Xs_DjC7OOSLdUtY1oYpivKD6hLMefk-4dnKLF_srFX5_b_bKrq9eMfPmjuw6iAOAD7ONbx5R_jsvfJDh7GMvz1k8qwhhGqCGWKNPWES_4befubXA</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Jia, Zhe</creator><creator>Zhang, Ke</creator><creator>Huang, RongHai</creator><creator>Zhou, XinGang</creator><creator>Jiang, Li</creator><general>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170101</creationdate><title>Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature</title><author>Jia, Zhe ; Zhang, Ke ; Huang, RongHai ; Zhou, XinGang ; Jiang, Li</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3555-83fa854b2303790d379cca387ad1d01ca818cbadca494ef51c3448f859c4640c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Carcinosarcoma - pathology</topic><topic>Carcinosarcoma - therapy</topic><topic>Clinical Case Report</topic><topic>Female</topic><topic>Humans</topic><topic>Pancreas - pathology</topic><topic>Pancreatic Neoplasms - pathology</topic><topic>Pancreatic Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jia, Zhe</creatorcontrib><creatorcontrib>Zhang, Ke</creatorcontrib><creatorcontrib>Huang, RongHai</creatorcontrib><creatorcontrib>Zhou, XinGang</creatorcontrib><creatorcontrib>Jiang, Li</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jia, Zhe</au><au>Zhang, Ke</au><au>Huang, RongHai</au><au>Zhou, XinGang</au><au>Jiang, Li</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>96</volume><issue>4</issue><spage>e5966</spage><epage>e5966</epage><pages>e5966-e5966</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>We report a rare case of pancreatic carcinosarcoma involving a 44-year-old woman. The patient complained of discomfort associated with the upper abdomen and jaundice of skin and sclera for 1 week.
After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of the pancreatic head.
Whipple procedure was conducted in May 2013. Intraoperative exploration indicated 2 components of the tumor: a fish-shaped gray matter and a hard structure similar to cancellous bone. Histopathological examination showed adenocarcinoma and osteosarcoma. After surgery, the patient received 8 cycles of chemotherapy with gemcitabine and raltitrexed.
Previous studies indicated poor prognosis for pancreatic carcinosarcoma. However, our patient survived for 31 months with no recurrence till date.
Coexistence of pancreatic adenocarcinoma and osteosarcoma is very rare. Our case was also an exception in manifesting longer survival than expected.</abstract><cop>United States</cop><pub>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>28121946</pmid><doi>10.1097/MD.0000000000005966</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Medicine (Baltimore), 2017-01, Vol.96 (4), p.e5966-e5966 |
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| source | Wolters Kluwer Open Health; MEDLINE; DOAJ Directory of Open Access Journals; IngentaConnect Free/Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Carcinosarcoma - pathology Carcinosarcoma - therapy Clinical Case Report Female Humans Pancreas - pathology Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy |
| title | Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature |
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