The native TRPP2-dependent channel of murine renal primary cilia

Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening monogenic renal disease. ADPKD results from mutations in either of two proteins: polycystin-1 (also known as PC1 or PKD1) or transient receptor potential cation channel, subfamily P, member 2 (TRPP2, also known...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2017-01, Vol.312 (1), p.F96-F108
Hauptverfasser:	Kleene, Steven J, Kleene, Nancy K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Cell Line Cells Cilia - metabolism Cytoplasm Cytoplasm - metabolism Epithelial Cells - metabolism Gene Knockout Techniques - methods Kidney - metabolism Kidney diseases Mice Permeability Polycystic Kidney, Autosomal Dominant - metabolism Proteins TRPP Cation Channels - genetics TRPP Cation Channels - metabolism
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