Long noncoding RNA HIT000218960 promotes papillary thyroid cancer oncogenesis and tumor progression by upregulating the expression of high mobility group AT-hook 2 (HMGA2) gene

Accumulating evidence suggests that long noncoding RNAs (lncRNAs) play an important role in oncogenesis and tumor progression. However, our knowledge of lncRNAs in thyroid cancer is still limited. To explore the crucial lncRNAs involved in oncogenesis of papillary thyroid cancer (PTC), we acquired d...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2017-01, Vol.16 (2), p.224-231
Hauptverfasser:	Li, Tao, Yang, Xiao-Dong, Ye, Chun-Xiang, Shen, Zhan-Long, Yang, Yang, Wang, Bo, Guo, Peng, Gao, Zhi-Dong, Ye, Ying-Jiang, Jiang, Ke-Wei, Wang, Shan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Carcinogenesis - genetics Carcinogenesis - pathology Carcinoma - genetics Carcinoma - pathology Carcinoma, Papillary Cell Line, Tumor Cell Movement - genetics Cell Proliferation Disease Progression Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Ontology HMGA2 Protein - genetics HMGA2 Protein - metabolism Humans Lymphatic Metastasis - genetics Lymphatic Metastasis - pathology Male Middle Aged Neoplasm Invasiveness Neoplasm Staging Oligonucleotide Array Sequence Analysis Reproducibility of Results RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Thyroid Cancer, Papillary Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Tumor Stem Cell Assay Up-Regulation - genetics
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