Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals

Functional delivery of mRNA to tissues in the body is key to implementing fundamentally new and potentially transformative strategies for vaccination, protein replacement therapy, and genome editing, collectively affecting approaches for the prevention, detection, and treatment of disease. Broadly a...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2017-01, Vol.114 (4), p.E448-E456
Hauptverfasser: McKinlay, Colin J., Vargas, Jessica R., Blake, Timothy R., Hardy, Jonathan W., Kanada, Masamitsu, Contag, Christopher H., Wender, Paul A., Waymouth, Robert M.
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Sprache:eng
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