Neuropsychiatric characteristics of GBA-associated Parkinson disease

Abstract Mutations in GBA1 are a well-established risk factor for Parkinson disease (PD). GBA-associated PD (GBA-PD) may have a higher burden of nonmotor symptoms than idiopathic PD (IPD). We sought to characterize the relationship between GBA-PD and neuropsychiatric symptoms. Subjects were screened...

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Veröffentlicht in:	Journal of the neurological sciences 2016-11, Vol.370, p.63-69
Hauptverfasser:	Swan, Matthew, MD, Doan, Nancy, Ortega, Robert A., MS, Barrett, Matthew, MD, Nichols, William, PhD, Ozelius, Laurie, PhD, Soto-Valencia, Jeannie, BA, Boschung, Sarah, BSN, Deik, Andres, MD, Sarva, Harini, MD, Cabassa, Jose, MD, Johannes, Brooke, MSc, MS, CGC, Raymond, Deborah, MS, CGC, Marder, Karen, MD, MPH, Giladi, Nir, MD, Miravite, Joan, FNP, Severt, William, MD, PhD, Sachdev, Rivka, MD, Shanker, Vicki, MD, Bressman, Susan, MD, Saunders-Pullman, Rachel, MD, MPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anxiety Anxiety - complications Anxiety - genetics Anxiety - physiopathology beta-Glucosidase - genetics Comorbidity Depression Depression - complications Depression - genetics Depression - physiopathology Disability Evaluation Female GBA1 Genetic Association Studies Genetic Predisposition to Disease Glucocerebrosidase Glucosylceramidase Heterozygote Humans Male Middle Aged Mutation Neurology Neuropsychological Tests Parkinson disease Parkinson Disease - complications Parkinson Disease - genetics Parkinson Disease - physiopathology Parkinson Disease - psychology Psychiatric Status Rating Scales Severity of Illness Index Sex Factors Tertiary Care Centers Time Factors
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