Host Cell Copper Transporters CTR1 and ATP7A are important for Influenza A virus replication

The essential role of copper in eukaryotic cellular physiology is known, but has not been recognized as important in the context of influenza A virus infection. In this study, we investigated the effect of cellular copper on influenza A virus replication. Influenza A/WSN/33 (H1N1) virus growth and m...

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Veröffentlicht in:	Virology journal 2017-01, Vol.14 (1), p.11-11, Article 11
Hauptverfasser:	Rupp, Jonathan C, Locatelli, Manon, Grieser, Alexis, Ramos, Andrea, Campbell, Patricia J, Yi, Hong, Steel, John, Burkhead, Jason L, Bortz, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Analysis Cation Transport Proteins - metabolism Cell Line copper Copper - metabolism Copper in the body Copper Transporter 1 Copper-Transporting ATPases culture media Culture Media - chemistry drugs Epithelial Cells - metabolism Epithelial Cells - virology genes Health aspects homeostasis Host-Pathogen Interactions Humans influenza Influenza A virus Influenza A Virus, H1N1 Subtype - physiology Influenza viruses microbial growth nucleoproteins pathogenesis RNA RNA interference sialidase transmission electron microscopy transporters virion Virus Replication
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