Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort

Prenatal exposure to lead (Pb) is known to decrease fetal growth; but its effects on postnatal growth and mechanistic insights linking Pb to growth are not clearly defined. Genomically imprinted genes are powerful regulators of growth and energy utilization, and may be particularly vulnerable to env...

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Veröffentlicht in:	Environmental Epigenetics 2016-01, Vol.2 (1)
Hauptverfasser:	Nye, Monica D., King, Katherine E., Darrah, Thomas H., Maguire, Rachel, Jima, Dereje D., Huang, Zhiqing, Mendez, Michelle A., Fry, Rebecca C., Jirtle, Randy L., Murphy, Susan K., Hoyo, Cathrine
Format:	Artikel
Sprache:	eng
Schlagworte:	Environmental aspects Fetal development Genetic aspects Health aspects Lead in the body Methylation RNA
Online-Zugang:	Volltext
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