Bacterial competition and quorum‐sensing signalling shape the eco‐evolutionary outcomes of model in vitro phage therapy

The rapid rise of antibiotic resistance has renewed interest in phage therapy – the use of bacteria‐specific viruses (phages) to treat bacterial infections. Even though phages are often pathogen‐specific, little is known about the efficiency and eco‐evolutionary outcomes of phage therapy in polymicr...

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Veröffentlicht in:	Evolutionary applications 2017-02, Vol.10 (2), p.161-169
Hauptverfasser:	Mumford, Rachel, Friman, Ville‐Petri
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Antibiotic resistance Antibiotics Bacteria Bacterial infections Clinical trials coevolution Competition cost of resistance Cystic fibrosis Evolution Gene expression Genotype & phenotype Genotypes host–parasite interactions Infections Mutation Original Pathogens phage therapy Phages polymicrobial infections Pseudomonas aeruginosa quorum‐sensing signalling resistance Staphylococcus aureus Stenotrophomonas
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