Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity

Considerable evidence has shown that neuroinflammation and oxidative stress play an important role in the pathophysiology of postoperative cognitive dysfunction (POCD) and other progressive neurodegenerative disorders. Increasing evidence suggests that acetaminophen (APAP) has unappreciated antioxid...

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Veröffentlicht in:	Journal of neuroinflammation 2017-01, Vol.14 (1), p.17, Article 17
Hauptverfasser:	Zhao, Wei-Xing, Zhang, Jun-Han, Cao, Jiang-Bei, Wang, Wei, Wang, Dong-Xin, Zhang, Xiao-Ying, Yu, Jun, Zhang, Yong-Yi, Zhang, You-Zhi, Mi, Wei-Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - pharmacology Animals Antioxidants Antioxidants - pharmacology Cognition disorders Cognitive Dysfunction - chemically induced Dosage and administration Drug therapy Hippocampus - drug effects Lipopolysaccharides Lipopolysaccharides - toxicity Male Maze Learning - drug effects Mice Mice, Inbred C57BL Motor Activity - drug effects Neuroprotective Agents - pharmacology
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