c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

The mRNA cap is a structure added to RNA pol II transcripts in eukaryotes, which recruits factors involved in RNA processing, nuclear export and translation initiation. RNA guanine-7 methyltransferase (RNMT)-RNA-activating miniprotein (RAM), the mRNA cap methyltransferase complex, completes the basi...

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Veröffentlicht in:	Biochemical journal 2017-02, Vol.474 (3), p.377-384
Hauptverfasser:	Dunn, Sianadh, Lombardi, Olivia, Cowling, Victoria H
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Nucleus Chromatin - chemistry Chromatin - metabolism HeLa Cells Humans Methylation Methyltransferases - genetics Methyltransferases - metabolism Protein Biosynthesis Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Ribosomes - chemistry Ribosomes - metabolism RNA Caps - chemistry RNA Caps - genetics RNA Caps - metabolism RNA Polymerase I - genetics RNA Polymerase I - metabolism RNA Polymerase II - genetics RNA Polymerase II - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Ribosomal - genetics RNA, Ribosomal - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Transcription, Genetic
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