Selection-, age-, and exercise-dependence of skeletal muscle gene expression patterns in a rat model of metabolic fitness

Intrinsic aerobic exercise capacity can influence many complex traits including obesity and aging. To study this connection we established two rat lines by divergent selection of untrained aerobic capacity. After 32 generations the high capacity runners (HCR) and low capacity runners (LCR) differed...

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Veröffentlicht in:	Physiological genomics 2016-11, Vol.48 (11), p.816-825
Hauptverfasser:	Ren, Yu-Yu, Koch, Lauren G, Britton, Steven L, Qi, Nathan R, Treutelaar, Mary K, Burant, Charles F, Li, Jun Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Animals Call for Papers Female Gene Expression Profiling Gene Expression Regulation, Developmental Models, Animal Muscle, Skeletal - metabolism Physical Conditioning, Animal Principal Component Analysis Rats
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