An Automated Test of Rat Forelimb Supination Quantifies Motor Function Loss and Recovery After Corticospinal Injury

Background. Rodents are the primary animal model of corticospinal injury and repair, yet current behavioral tests do not show the large deficits after injury observed in humans. Forearm supination is critical for hand function and is highly impaired by corticospinal injury in both humans and rats. C...

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Veröffentlicht in:	Neurorehabilitation and neural repair 2017-02, Vol.31 (2), p.122-132
Hauptverfasser:	Sindhurakar, Anil, Butensky, Samuel D., Meyers, Eric, Santos, Joshua, Bethea, Thelma, Khalili, Ashley, Sloan, Andrew P., Rennaker, Robert L., Carmel, Jason B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Automation, Laboratory Disease Models, Animal Equipment Design Female Food Forelimb - physiopathology Motor Cortex - injuries Motor Cortex - physiopathology Motor Skills Movement Disorders - diagnosis Movement Disorders - etiology Movement Disorders - physiopathology Muscimol Pyramidal Tracts - injuries Pyramidal Tracts - physiopathology Rats, Sprague-Dawley Recovery of Function Severity of Illness Index Spinal Cord Injuries - complications Spinal Cord Injuries - diagnosis Spinal Cord Injuries - physiopathology Supination
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