Convection-enhanced Delivery of Therapeutics for Malignant Gliomas

Convection-enhanced delivery (CED) circumvents the blood–brain barrier by delivering agents directly into the tumor and surrounding parenchyma. CED can achieve large volumes of distribution by continuous positive-pressure infusion. Although promising as an effective drug delivery method in concept,...

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Veröffentlicht in:	Neurologia medico-chirurgica 2017, Vol.57(1), pp.8-16
Hauptverfasser:	SAITO, Ryuta, TOMINAGA, Teiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use blood–brain barrier Brain Neoplasms - drug therapy Chemotherapy Clinical trials Convection convection-enhanced delivery Drug delivery Drug Delivery Systems Glioma - drug therapy Humans malignant glioma Parenchyma Review
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