Characterization of Naturally Processed Antigen Bound to Major Histocompatibility Complex Class II Molecules

Helper T lymphocytes recognize peptide fragments of antigen bound to major histocompatibility complex (MHC) class II molecules presented on the surface of antigen-presenting cells (APCs). Previous studies showed that the MHC class II, I-Ekmolecules purified from APCs that had processed Drosophila me...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-09, Vol.88 (18), p.7928-7932
Hauptverfasser:	Srinivasan, Mallika, Marsh, Eric W., Pierce, Susan K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animals Antigen-Presenting Cells - metabolism Antigenic determinants, haptens, artificial antigens Antigens Antigens - metabolism Biological and medical sciences Cell lines Cytochrome c Group - chemistry Cytochrome c Group - immunology Cytochrome c Group - metabolism Cytochromes Fundamental and applied biological sciences. Psychology Fundamental immunology H-2 Antigens - metabolism Histocompatibility Antigens Class II - metabolism Methylation Mice Molecular immunology Molecular Sequence Data Molecular Weight Molecules Protein Binding Proteins Radioactive decay Recombinant Proteins T lymphocytes T-Lymphocytes - metabolism
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